Treatment-Resistant Depression Care for Centennial, Colorado

If you live in Centennial and two or more antidepressants haven’t brought relief, a comprehensive evaluation can help clarify the next step. TMS, Spravato®, and IV ketamine are available under one psychiatrist’s clinical direction at our Littleton clinic, about 16 minutes away along C-470, with evaluations and follow-ups available by telehealth.

A broader evaluation for treatment-resistant depression

For some people, TMS is the right next step. Others may be better served by a medication change, Spravato®, IV ketamine, a psychotherapy referral, or further diagnostic review. A comprehensive evaluation considers those options before recommending a treatment.

At Fortifying Wellness, the psychiatrist who completes your evaluation also directs TMS, Spravato®, and IV ketamine care. Depression is generally considered treatment-resistant after two or more adequate antidepressant trials; the treatment-resistant depression hub covers the options in depth. The short version:

  • TMS therapy: non-invasive treatment without anesthesia; device, protocol, and coverage criteria vary
  • Spravato®: FDA-approved for treatment-resistant depression, taken in our monitored office
  • IV ketamine: physician-directed infusions; FDA-approved as an anesthetic, used off-label for depression

How care works when you’re coming from Centennial

The free consultation and the comprehensive evaluation can both happen by secure telehealth from home. In-person treatment (TMS sessions, Spravato® doses, infusions) happens at 7345 S. Pierce St in Littleton, about 16 minutes west along C-470. TMS visits in particular are brief, and the reverse-commute direction keeps the drive predictable.

Also serving Highlands Ranch, Lone Tree, and Greenwood Village

The same care model applies across the south metro area. Coming from Highlands Ranch? See our Highlands Ranch page. Wherever you’re starting from, we verify your insurance benefits before you commit to anything.

Medically reviewed by Eric Wagner, MD, Psychiatrist & Medical Director · Last reviewed August 2026

Common Questions

Centennial FAQs

Where do Centennial patients go for treatment-resistant depression care?

Our Littleton clinic is about 16 minutes from Centennial along C-470 and offers TMS, Spravato®, and IV ketamine with one psychiatrist doing both the evaluation and the treatment. Evaluations and follow-ups can happen by telehealth from home.

Can I do my appointments by telehealth?

Evaluations, medication management, and follow-ups: yes, by secure video anywhere in Colorado. TMS sessions, Spravato® doses, and ketamine infusions happen in person at our Littleton office because they require in-office administration and monitoring.

Is this covered by insurance?

Coverage for TMS and Spravato® depends on your specific plan and prior-authorization criteria; IV ketamine for depression is off-label and is typically self-pay. We verify benefits and provide a written estimate before treatment begins. Insurance details →

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Start from Centennial with one free conversation

Your history heard, your questions answered, your benefits verified, by telehealth or in person, whichever you prefer.

7345 S. Pierce St, Suite 205, Littleton, CO 80128 · Serving Littleton, Ken Caryl, Columbine, Highlands Ranch, Centennial, Lone Tree, Englewood, Lakewood & the south Denver metro